Type of genetic disorder:
Angelman Syndrome is caused by a mutation on the maternally inherited chromosome 15. It is caused by a deletion or inactivation of critical genes on that chromosome. The mutation on the gene is usually caused by random events during the formation of reproductive cells or in early fetal development. Affected people usually have no history of the disorder in their family. It can be inherited, but it is usually developed. It is an autosomal dominant disease.
Some symptoms/effects of the disease are:
Feeding problems during infancy.
Delay in sitting and walking.
Absent or little speech.
Poor attention span and hyperactivity.
Severe learning disabilities.
Epilepsy.
Unusual, jerky movements.
Affectionate nature and frequent laughter.
Wide based, stiff-legged gait.
Below average head size.
Flattened back.
Subtle, yet sometimes characteristic facial features.
Poor sleeping pattern.
Crossed eyes.
Scoliosis.
Increased sensitivity to heat.
Attraction to water.
A few ways to diagnose someone with Angelman Syndrome are:
Checking for early developmental delay.
By using genetic tests.
The diagnosis is usually confirmed, in most cases, by age three. The prognosis for Angelman Syndrome is:
Severe developmental delays
Speech limitations
Motor difficulties
Normal life span
No developmental regression with age
The treatment for the disease is usually not specific, but these procedures are often used:
Medical therapy for seizures.
Physical & Occupational Therapy.
Speech Therapy.
Behavioral Therapy.
Other Info:
Colin Farrel's child has Angelman Syndrome.
A person with Angelman Syndrome would have a structurally normal brain while using a CT or an MRI scan.
Also known as Happy Puppet Syndrome due to frequent laughter, a happy demeanor, and an easily excitable personality. They also would have flapping hand motions, hyperactive behavior, and a short attention span.
You can find some depictions of Angelman Syndrome at the following sites:
A depiction of chromosomes affected by Angelman Syndrome.
Comments:
I think you should have the pictures on your page, instead of having a link, but other then that, it looks pretty good. Happy Puppet Syndrome??
-Cretinism
The italicized font is somewhat difficult to read, and the page could benefit form some pictures posted directly on it. Other than that, good job. - Albinism
Your Website looks good, I agree with the writer of the Albinism comment, the writing is a little tricky to read. Don't forget your pictures! Also, don't forget to write sentences if you want full credit. Very good facts by the way. I think that's sad that they call Angelman Syndrome "Happy Puppet Syndrome" that is just mean! Great job guys!~ Turner's Syndrome (SL&KT)
Wow, your page looks great, its very colorful. We think its sad that there aren't many treatment options. - Marfan's Syndrome
This page is very colorful and fun. The use of color makes it easy to distinguish between the sections. The information is very in depth, but you forgot pictures. We corrected the spelling of "structurally" under "other info". Other than that great job. PR & EN
The page looks very nice and colorful. We think that it is sad that this disease is inherited from the mothers, it makes the mommies look like the bad person. Also, we thought that maybe some pictures would help explain this better. But other than that, great job! Cri-du-Chat (RS and UP)
I agree with the others who have commented on this page: the font is a little hard to read. Plus, the multiple colors are a little dizzying and distracting. I also added a hyphen between "stiff" and "legged". I wonder why it is called Angelman Syndrome? Also, does anyone ever die from it? Can they lead a normal life? Those are a few things you might want to find out for the prognosis section. It's interesting that people who have this disorder have no history of it in their family. - HEMOPHILIA
WOW! This is amazing. Nice colors. It is so cool that they are attracted to water!!!!!!!!!!!! DK and EE
Woahh. It looks like you put a lot of effort into your page. It's very detailed and stuff. Keep up the good work. =D Love, HK & JM
It's a fine page when it comes to information, but the multiple text sizes and colors is confusing. And the lack of pictures. We like us some pictures. -JH & CL
Angelman Syndrome is caused by a mutation on the maternally inherited chromosome 15. It is caused by a deletion or inactivation of critical genes on that chromosome. The mutation on the gene is usually caused by random events during the formation of reproductive cells or in early fetal development. Affected people usually have no history of the disorder in their family. It can be inherited, but it is usually developed. It is an autosomal dominant disease.
Some symptoms/effects of the disease are:
A few ways to diagnose someone with Angelman Syndrome are:
- Checking for early developmental delay.
- By using genetic tests.
The diagnosis is usually confirmed, in most cases, by age three.The prognosis for Angelman Syndrome is:
The treatment for the disease is usually not specific, but these procedures are often used:
Other Info:
You can find some depictions of Angelman Syndrome at the following sites:
- http://www.ourangeltyler.com/db4/00400/ourangeltyler.com/_uimages/TY0303.jpg
A child with Angelman Syndrome.- http://www.bcm.edu/fromthelab/vol02/is4/images/hippocampus.jpg</span>
A picture of the section of the brain affected by Angelman Syndrome.- http://asclepius.com/angel/factso1.gif
A depiction of chromosomes affected by Angelman Syndrome.Comments:
I think you should have the pictures on your page, instead of having a link, but other then that, it looks pretty good. Happy Puppet Syndrome??
-Cretinism
The italicized font is somewhat difficult to read, and the page could benefit form some pictures posted directly on it. Other than that, good job. - Albinism
Your Website looks good, I agree with the writer of the Albinism comment, the writing is a little tricky to read. Don't forget your pictures! Also, don't forget to write sentences if you want full credit. Very good facts by the way. I think that's sad that they call Angelman Syndrome "Happy Puppet Syndrome" that is just mean! Great job guys!~ Turner's Syndrome (SL&KT)
Wow, your page looks great, its very colorful. We think its sad that there aren't many treatment options. - Marfan's Syndrome
This page is very colorful and fun. The use of color makes it easy to distinguish between the sections. The information is very in depth, but you forgot pictures. We corrected the spelling of "structurally" under "other info". Other than that great job. PR & EN
The page looks very nice and colorful. We think that it is sad that this disease is inherited from the mothers, it makes the mommies look like the bad person. Also, we thought that maybe some pictures would help explain this better. But other than that, great job! Cri-du-Chat (RS and UP)
I agree with the others who have commented on this page: the font is a little hard to read. Plus, the multiple colors are a little dizzying and distracting. I also added a hyphen between "stiff" and "legged". I wonder why it is called Angelman Syndrome? Also, does anyone ever die from it? Can they lead a normal life? Those are a few things you might want to find out for the prognosis section. It's interesting that people who have this disorder have no history of it in their family. - HEMOPHILIA
WOW! This is amazing. Nice colors. It is so cool that they are attracted to water!!!!!!!!!!!! DK and EE
Woahh. It looks like you put a lot of effort into your page. It's very detailed and stuff. Keep up the good work. =D Love, HK & JM
It's a fine page when it comes to information, but the multiple text sizes and colors is confusing. And the lack of pictures. We like us some pictures. -JH & CL
Work's Cited:
"Angelman Syndrome." 27 Mar. 2008. 31 Mar. 2008 <**//http://en.wikipedia.org/wiki/Angelman_syndrome>.//**
"Angelman Syndrome." Genetics Home Reference: Your Guide to Understanding Genetic Conditions. 28 Mar. 2008. .S. National Library of Medicine. 31 Mar. 2008 <**//http://ghr.nlm.nih.gov/condition=angelmansyndrome>.//**
"Angelman Syndrome." Medicine Net. 16 Oct. 2007. National Institute of Neurological Disorders and Stroke. 31 Mar. 2008 <**//http://www.medicinenet.com/angelman_syndrome/article.htm>.//**
"Facts About Angelman Syndrome:." 18 Jan. 2002. 2 Apr. 2008 <**//http://asclepius.com/angel/asfinfo.html>.//**